TSR Labs

Dr. Sachdeva’s lab uses 3D culture models of human and mouse-derived cells to study the pathogenesis of esophageal cancer, with a focus on the role of the esophageal microenvironment in early-stage disease. We are a dynamic group of scientists and scientists-in-training from diverse backgrounds, with projects encompassing the fields of cancer cell biology, 3D epithelial organoid biology, cell metabolism and tumor-stromal interactions. Our goal is to gain better understanding of the molecular changes that accompany the development and progression of esophageal cancer, the eighth most common cancer worldwide and sixth most common cause of cancer deaths.